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Mouse Arf-GAP Rho-GAP domain ANK repeat PH domain-containing 3 (aa 1-1538 )

Centd3 Swiss Prot#

Q8R5G7

Centd3 Protein names

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3) (Dual specificity Rho- and Arf-GTPase-activating protein 1)

Centd3 Gene names

Arap3 Centd3 Drag1 Kiaa4097

Organism

Mus musculus (Mouse)

Centd3 Entry name

ARAP3_MOUSE

Centd3 Codon optimized cDNA(gene) Clone

Centd3 Cat #

RPY2543

Tag

Centd3 contains A 6x histidine tag

Centd3 Formulation

Liquid

Centd3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Centd3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Centd3 Protein

Centd3 Cat #

PY2543

Centd3 Source

recombinant

Centd3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Centd3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Centd3 Activity

N/A

Tag

Centd3 Contains A 6x histidine tag

Centd3 Formulation

Liquid

Centd3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Centd3 family

-

Centd3 Subcellular locations

Cytoplasm. Cell membrane; Peripheral membrane protein. Cytoplasm > cytoskeleton. Cell projection > lamellipodium. Cell projection > ruffle.

Centd3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Phosphatidylinositol-3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol-3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts preferentially on ARF5 and on RHOA.

Centd3 Sequence

DDBJ

EMBL

GenBank

Centd3 3D structure

ModBase

Centd3 interaction

STRING

Centd3 Proteomic

PRIDE

Centd3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Centd3 Organism specific

CTD

MGI

Centd3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Centd3 Gene expression

Bgee

ArrayExpress

Genevestigator

Centd3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY