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Human CLIP-associating protein 1 (aa 1-1538 )
CLASP1 Swiss Prot#
Q7Z460
CLASP1 Protein names
CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1) (Protein Orbit homolog 1) (hOrbit1)
CLASP1 Gene names
CLASP1 KIAA0622 MAST1
Organism
Homo sapiens (Human)
CLASP1 Entry name
CLAP1_HUMAN
CLASP1 Codon optimized cDNA(gene) Clone
CLASP1 Cat #
RPY2542
Tag
CLASP1 contains A 6x histidine tag
CLASP1 Formulation
Liquid
CLASP1 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
CLASP1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant CLASP1 Protein
CLASP1 Cat #
PY2542
CLASP1 Source
recombinant
CLASP1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
CLASP1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
CLASP1 Activity
N/A
Tag
CLASP1 Contains A 6x histidine tag
CLASP1 Formulation
Liquid
CLASP1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CLASP1 family
CLASP family
CLASP1 Subcellular locations
Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton > spindle. Golgi apparatus > trans-Golgi network.
CLASP1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
CLASP1 Sequence
DDBJ EMBL GenBank
CLASP1 3D structure
ModBase
CLASP1 interaction
STRING
CLASP1 Proteomic
PRIDE
CLASP1 Genome annotation
Ensembl GeneID KEGG UCSC
CLASP1 Organism specific
CTD MGI
CLASP1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CLASP1 Gene expression
Bgee ArrayExpress Genevestigator
CLASP1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY