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| Human CLIP-associating protein 1 (aa 1-1538 ) |
| CLASP1 Swiss Prot# | | Q7Z460 |
| CLASP1 Protein names | | CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1) (Protein Orbit homolog 1) (hOrbit1) |
| CLASP1 Gene names | | CLASP1 KIAA0622 MAST1 |
| Organism | | Homo sapiens (Human) |
| CLASP1 Entry name | | CLAP1_HUMAN |
| CLASP1 Codon optimized cDNA(gene) Clone |
| CLASP1 Cat # | | RPY2542 |
| Tag | | CLASP1 contains A 6x histidine tag |
| CLASP1 Formulation | | Liquid |
| CLASP1 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| CLASP1 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant CLASP1 Protein |
| CLASP1 Cat # | | PY2542 |
| CLASP1 Source | | recombinant |
| CLASP1 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| CLASP1 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| CLASP1 Activity | | N/A |
| Tag | | CLASP1 Contains A 6x histidine tag |
| CLASP1 Formulation | | Liquid |
| CLASP1 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CLASP1 Products | | For pricing and availability Click Here >>> |
| CLASP1 family | | CLASP family |
| CLASP1 Subcellular locations | | Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton > spindle. Golgi apparatus > trans-Golgi network. |
| CLASP1 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle. |
| CLASP1 Sequence | | DDBJ | EMBL | GenBank |
| CLASP1 3D structure | | ModBase |
| CLASP1 interaction | | STRING |
| CLASP1 Proteomic | | PRIDE |
| CLASP1 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| CLASP1 Organism specific | | CTD | MGI |
| CLASP1 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CLASP1 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| CLASP1 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |