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Human Rho guanine nucleotide exchange factor 11 (aa 1-1522 )

ARHGEF11 Swiss Prot#

O15085

ARHGEF11 Protein names

Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF)

ARHGEF11 Gene names

ARHGEF11 KIAA0380

Organism

Homo sapiens (Human)

ARHGEF11 Entry name

ARHGB_HUMAN

ARHGEF11 Codon optimized cDNA(gene) Clone

ARHGEF11 Cat #

RPY2538

Tag

ARHGEF11 contains A 6x histidine tag

ARHGEF11 Formulation

Liquid

ARHGEF11 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ARHGEF11 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ARHGEF11 Protein

ARHGEF11 Cat #

PY2538

ARHGEF11 Source

recombinant

ARHGEF11 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ARHGEF11 Purity

>90%, as determined by SDS-PAGE under reducing conditions

ARHGEF11 Activity

N/A

Tag

ARHGEF11 Contains A 6x histidine tag

ARHGEF11 Formulation

Liquid

ARHGEF11 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ARHGEF11 family

-

ARHGEF11 Subcellular locations

Cytoplasm. Membrane.

ARHGEF11 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.

ARHGEF11 Sequence

DDBJ

EMBL

GenBank

ARHGEF11 3D structure

ModBase

ARHGEF11 interaction

STRING

ARHGEF11 Proteomic

PRIDE

ARHGEF11 Genome annotation

Ensembl

GeneID

KEGG

UCSC

ARHGEF11 Organism specific

CTD

MGI

ARHGEF11 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ARHGEF11 Gene expression

Bgee

ArrayExpress

Genevestigator

ARHGEF11 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY