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Rat SH3 multiple ankyrin repeat domains protein 2 (aa 1-1474 )

Cortbp1 Swiss Prot#

Q9QX74

Cortbp1 Protein names

SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (GKAP/SAPAP-interacting protein) (Proline-rich synapse-associated protein 1) (ProSAP1) (SPANK-3)

Cortbp1 Gene names

Shank2 Cortbp1

Organism

Rattus norvegicus (Rat)

Cortbp1 Entry name

SHAN2_RAT

Cortbp1 Codon optimized cDNA(gene) Clone

Cortbp1 Cat #

RPY2525

Tag

Cortbp1 contains A 6x histidine tag

Cortbp1 Formulation

Liquid

Cortbp1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Cortbp1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Cortbp1 Protein

Cortbp1 Cat #

PY2525

Cortbp1 Source

recombinant

Cortbp1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Cortbp1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Cortbp1 Activity

N/A

Tag

Cortbp1 Contains A 6x histidine tag

Cortbp1 Formulation

Liquid

Cortbp1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Cortbp1 family

SHANK family

Cortbp1 Subcellular locations

Cytoplasm. Cell junction > synapse. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell projection > growth cone.

Cortbp1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.

Cortbp1 Sequence

DDBJ

EMBL

GenBank

Cortbp1 3D structure

ModBase

Cortbp1 interaction

STRING

Cortbp1 Proteomic

PRIDE

Cortbp1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Cortbp1 Organism specific

CTD

MGI

Cortbp1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Cortbp1 Gene expression

Bgee

ArrayExpress

Genevestigator

Cortbp1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY