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Human Arf-GAP Rho-GAP ANK repeat PH domain-containing 1 (aa 1-1450 )

CENTD2 Swiss Prot#

Q96P48

CENTD2 Protein names

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2)

CENTD2 Gene names

ARAP1 CENTD2 KIAA0782

Organism

Homo sapiens (Human)

CENTD2 Entry name

ARAP1_HUMAN

CENTD2 Codon optimized cDNA(gene) Clone

CENTD2 Cat #

RPY2514

Tag

CENTD2 contains A 6x histidine tag

CENTD2 Formulation

Liquid

CENTD2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CENTD2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CENTD2 Protein

CENTD2 Cat #

PY2514

CENTD2 Source

recombinant

CENTD2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CENTD2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CENTD2 Activity

N/A

Tag

CENTD2 Contains A 6x histidine tag

CENTD2 Formulation

Liquid

CENTD2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CENTD2 family

-

CENTD2 Subcellular locations

Cytoplasm. Golgi apparatus > Golgi stack membrane; Peripheral membrane protein. Cell membrane.

CENTD2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Phosphatidylinositol-3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol-3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 (By similarity).

CENTD2 Sequence

DDBJ

EMBL

GenBank

CENTD2 3D structure

ModBase

CENTD2 interaction

STRING

CENTD2 Proteomic

PRIDE

CENTD2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CENTD2 Organism specific

CTD

MGI

CENTD2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CENTD2 Gene expression

Bgee

ArrayExpress

Genevestigator

CENTD2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY