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Rat Deleted in malignant brain tumors 1 protein (aa 1-1418 )
Dmbt1 Swiss Prot#
Q8CIZ5
Dmbt1 Protein names
Deleted in malignant brain tumors 1 protein (Ebnerin) (Hensin) (Pancrin)
Dmbt1 Gene names
Dmbt1
Organism
Rattus norvegicus (Rat)
Dmbt1 Entry name
DMBT1_RAT
Dmbt1 Codon optimized cDNA(gene) Clone
Dmbt1 Cat #
RPY2500
Tag
Dmbt1 contains A 6x histidine tag
Dmbt1 Formulation
Liquid
Dmbt1 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Dmbt1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Dmbt1 Protein
Dmbt1 Cat #
PY2500
Dmbt1 Source
recombinant
Dmbt1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Dmbt1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
Dmbt1 Activity
N/A
Tag
Dmbt1 Contains A 6x histidine tag
Dmbt1 Formulation
Liquid
Dmbt1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Dmbt1 family
DMBT1 family
Dmbt1 Subcellular locations
Secreted. Cytoplasmic vesicle > secretory vesicle membrane; Single-pass membrane protein; Lumenal side.
Dmbt1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: May play roles in mucosal defense system, cellular immune defense and epithelial differentiation (By similarity). May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophages tissues throughout the body, including epithelial cells lining the gastrointestinal tract (By similarity). Required for terminal differentiation of columnar epithelial cells during early embryogenesis. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell (By similarity).
Dmbt1 Sequence
DDBJ EMBL GenBank
Dmbt1 3D structure
ModBase
Dmbt1 interaction
STRING
Dmbt1 Proteomic
PRIDE
Dmbt1 Genome annotation
Ensembl GeneID KEGG UCSC
Dmbt1 Organism specific
CTD MGI
Dmbt1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Dmbt1 Gene expression
Bgee ArrayExpress Genevestigator
Dmbt1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY