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Human Uveal autoantigen coiled-coil domains ankyrin repeats (aa 1-1416 )

UACA Swiss Prot#

Q9BZF9

UACA Protein names

Uveal autoantigen with coiled-coil domains and ankyrin repeats

UACA Gene names

UACA KIAA1561

Organism

Homo sapiens (Human)

UACA Entry name

UACA_HUMAN

UACA Codon optimized cDNA(gene) Clone

UACA Cat #

RPY2499

Tag

UACA contains A 6x histidine tag

UACA Formulation

Liquid

UACA Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

UACA Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant UACA Protein

UACA Cat #

PY2499

UACA Source

recombinant

UACA Applications

Western Blot, SDS-Page or may be used for other applications determined by user

UACA Purity

>90%, as determined by SDS-PAGE under reducing conditions

UACA Activity

N/A

Tag

UACA Contains A 6x histidine tag

UACA Formulation

Liquid

UACA Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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UACA family

-

UACA Subcellular locations

Nucleus. Cytoplasm. Cytoplasm > cytoskeleton.

UACA FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).; FUNCTION: Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury (By similarity).

UACA Sequence

DDBJ

EMBL

GenBank

UACA 3D structure

ModBase

UACA interaction

STRING

UACA Proteomic

PRIDE

UACA Genome annotation

Ensembl

GeneID

KEGG

UCSC

UACA Organism specific

CTD

MGI

UACA Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

UACA Gene expression

Bgee

ArrayExpress

Genevestigator

UACA Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY