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Human Leucine-rich PPR motif-containing mitochondrial (aa 1-1394 )

LRP130 Swiss Prot#

P42704

LRP130 Protein names

Leucine-rich PPR motif-containing protein, mitochondrial (130 kDa leucine-rich protein) (LRP 130) (GP130)

LRP130 Gene names

LRPPRC LRP130

Organism

Homo sapiens (Human)

LRP130 Entry name

LPPRC_HUMAN

LRP130 Codon optimized cDNA(gene) Clone

LRP130 Cat #

RPY2483

Tag

LRP130 contains A 6x histidine tag

LRP130 Formulation

Liquid

LRP130 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

LRP130 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant LRP130 Protein

LRP130 Cat #

PY2483

LRP130 Source

recombinant

LRP130 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

LRP130 Purity

>90%, as determined by SDS-PAGE under reducing conditions

LRP130 Activity

N/A

Tag

LRP130 Contains A 6x histidine tag

LRP130 Formulation

Liquid

LRP130 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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LRP130 family

-

LRP130 Subcellular locations

Mitochondrion. Nucleus > nucleoplasm. Nucleus inner membrane. Nucleus outer membrane.

LRP130 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).

LRP130 Sequence

DDBJ

EMBL

GenBank

LRP130 3D structure

ModBase

LRP130 interaction

STRING

LRP130 Proteomic

PRIDE

LRP130 Genome annotation

Ensembl

GeneID

KEGG

UCSC

LRP130 Organism specific

CTD

MGI

LRP130 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

LRP130 Gene expression

Bgee

ArrayExpress

Genevestigator

LRP130 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY