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Rat Leucine-rich PPR motif-containing mitochondrial (aa 1-1392 )
Lrp157 Swiss Prot#
Q5SGE0
Lrp157 Protein names
Leucine-rich PPR motif-containing protein, mitochondrial (130 kDa leucine-rich protein) (LRP 130) (Leucine rich protein 157) (rLRP157)
Lrp157 Gene names
Lrpprc Lrp157
Organism
Rattus norvegicus (Rat)
Lrp157 Entry name
LPPRC_RAT
Lrp157 Codon optimized cDNA(gene) Clone
Lrp157 Cat #
RPY2482
Tag
Lrp157 contains A 6x histidine tag
Lrp157 Formulation
Liquid
Lrp157 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Lrp157 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Lrp157 Protein
Lrp157 Cat #
PY2482
Lrp157 Source
recombinant
Lrp157 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Lrp157 Purity
>90%, as determined by SDS-PAGE under reducing conditions
Lrp157 Activity
N/A
Tag
Lrp157 Contains A 6x histidine tag
Lrp157 Formulation
Liquid
Lrp157 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Lrp157 family
-
Lrp157 Subcellular locations
Mitochondrion. Nucleus. Nucleus > nucleoplasm. Nucleus inner membrane. Nucleus outer membrane.
Lrp157 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).
Lrp157 Sequence
DDBJ EMBL GenBank
Lrp157 3D structure
ModBase
Lrp157 interaction
STRING
Lrp157 Proteomic
PRIDE
Lrp157 Genome annotation
Ensembl GeneID KEGG UCSC
Lrp157 Organism specific
CTD MGI
Lrp157 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Lrp157 Gene expression
Bgee ArrayExpress Genevestigator
Lrp157 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY