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Mouse Eukaryotic translation initiation factor 3 subunit A (aa 1-1344 )
Csma Swiss Prot#
P23116
Csma Protein names
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Centrosomin) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (p162)
Csma Gene names
Eif3a Csma Eif3 Eif3s10
Organism
Mus musculus (Mouse)
Csma Entry name
EIF3A_MOUSE
Csma Codon optimized cDNA(gene) Clone
Csma Cat #
RPY2466
Tag
Csma contains A 6x histidine tag
Csma Formulation
Liquid
Csma Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Csma Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Csma Protein
Csma Cat #
PY2466
Csma Source
recombinant
Csma Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Csma Purity
>90%, as determined by SDS-PAGE under reducing conditions
Csma Activity
N/A
Tag
Csma Contains A 6x histidine tag
Csma Formulation
Liquid
Csma Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Csma family
EIF-3 subunit A family
Csma Subcellular locations
Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Nucleus.
Csma FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Csma Sequence
DDBJ EMBL GenBank
Csma 3D structure
ModBase
Csma interaction
STRING
Csma Proteomic
PRIDE
Csma Genome annotation
Ensembl GeneID KEGG UCSC
Csma Organism specific
CTD MGI
Csma Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Csma Gene expression
Bgee ArrayExpress Genevestigator
Csma Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY