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Rat Partitioning defective 3 homolog (aa 1-1337 )

Par3 Swiss Prot#

Q9Z340

Par3 Protein names

Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Atypical PKC-specific-binding protein) (ASBP)

Par3 Gene names

Pard3 Par3

Organism

Rattus norvegicus (Rat)

Par3 Entry name

PARD3_RAT

Par3 Codon optimized cDNA(gene) Clone

Par3 Cat #

RPY2460

Tag

Par3 contains A 6x histidine tag

Par3 Formulation

Liquid

Par3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Par3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Par3 Protein

Par3 Cat #

PY2460

Par3 Source

recombinant

Par3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Par3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Par3 Activity

N/A

Tag

Par3 Contains A 6x histidine tag

Par3 Formulation

Liquid

Par3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Par3 family

PAR3 family

Par3 Subcellular locations

Endomembrane system. Cell junction. Cell junction > tight junction. Cytoplasm > cell cortex. Cytoplasm > cytoskeleton.

Par3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (By similarity). Targets the phosphatase PTEN to cell junctions.

Par3 Sequence

DDBJ

EMBL

GenBank

Par3 3D structure

ModBase

Par3 interaction

STRING

Par3 Proteomic

PRIDE

Par3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Par3 Organism specific

CTD

MGI

Par3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Par3 Gene expression

Bgee

ArrayExpress

Genevestigator

Par3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY