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Rat Ras GTPase-activating protein SynGAP (aa 1-1308 )

Syngap1 Swiss Prot#

Q9QUH6

Syngap1 Protein names

Ras GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1) (p135 SynGAP)

Syngap1 Gene names

Syngap1

Organism

Rattus norvegicus (Rat)

Syngap1 Entry name

SYGP1_RAT

Syngap1 Codon optimized cDNA(gene) Clone

Syngap1 Cat #

RPY2447

Tag

Syngap1 contains A 6x histidine tag

Syngap1 Formulation

Liquid

Syngap1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Syngap1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Syngap1 Protein

Syngap1 Cat #

PY2447

Syngap1 Source

recombinant

Syngap1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Syngap1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Syngap1 Activity

N/A

Tag

Syngap1 Contains A 6x histidine tag

Syngap1 Formulation

Liquid

Syngap1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Syngap1 family

-

Syngap1 Subcellular locations

Membrane; Peripheral membrane protein. Cell junction > synapse.

Syngap1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits.

Syngap1 Sequence

DDBJ

EMBL

GenBank

Syngap1 3D structure

ModBase

Syngap1 interaction

STRING

Syngap1 Proteomic

PRIDE

Syngap1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Syngap1 Organism specific

CTD

MGI

Syngap1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Syngap1 Gene expression

Bgee

ArrayExpress

Genevestigator

Syngap1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY