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Mouse CLIP-associating protein 2 (aa 1-1286 )

Clasp2 Swiss Prot#

Q8BRT1

Clasp2 Protein names

CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2)

Clasp2 Gene names

Clasp2 Kiaa0627

Organism

Mus musculus (Mouse)

Clasp2 Entry name

CLAP2_MOUSE

Clasp2 Codon optimized cDNA(gene) Clone

Clasp2 Cat #

RPY2439

Tag

Clasp2 contains A 6x histidine tag

Clasp2 Formulation

Liquid

Clasp2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Clasp2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Clasp2 Protein

Clasp2 Cat #

PY2439

Clasp2 Source

recombinant

Clasp2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Clasp2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Clasp2 Activity

N/A

Tag

Clasp2 Contains A 6x histidine tag

Clasp2 Formulation

Liquid

Clasp2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Clasp2 family

CLASP family

Clasp2 Subcellular locations

Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole. Golgi apparatus. Golgi apparatus > trans-Golgi network.

Clasp2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Clasp2 Sequence

DDBJ

EMBL

GenBank

Clasp2 3D structure

ModBase

Clasp2 interaction

STRING

Clasp2 Proteomic

PRIDE

Clasp2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Clasp2 Organism specific

CTD

MGI

Clasp2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Clasp2 Gene expression

Bgee

ArrayExpress

Genevestigator

Clasp2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY