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Mouse Protein diaphanous homolog 1 (aa 1-1255 )

Diap1 Swiss Prot#

O08808

Diap1 Protein names

Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (p140mDIA) (mDIA1)

Diap1 Gene names

Diaph1 Diap1

Organism

Mus musculus (Mouse)

Diap1 Entry name

DIAP1_MOUSE

Diap1 Codon optimized cDNA(gene) Clone

Diap1 Cat #

RPY2416

Tag

Diap1 contains A 6x histidine tag

Diap1 Formulation

Liquid

Diap1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Diap1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Diap1 Protein

Diap1 Cat #

PY2416

Diap1 Source

recombinant

Diap1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Diap1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Diap1 Activity

N/A

Tag

Diap1 Contains A 6x histidine tag

Diap1 Formulation

Liquid

Diap1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Diap1 family

Formin homology family, Diaphanous subfamily

Diap1 Subcellular locations

Cell membrane. Cell projection > ruffle membrane. Cytoplasm > cytoskeleton.

Diap1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and promote cell migration. Has neurite outgrowth promoting activity.

Diap1 Sequence

DDBJ

EMBL

GenBank

Diap1 3D structure

ModBase

Diap1 interaction

STRING

Diap1 Proteomic

PRIDE

Diap1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Diap1 Organism specific

CTD

MGI

Diap1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Diap1 Gene expression

Bgee

ArrayExpress

Genevestigator

Diap1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY