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Rat Membrane-associated phosphatidylinositol transfer 1 (aa 1-1242 )

Nir2 Swiss Prot#

Q5U2N3

Nir2 Protein names

Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2)

Nir2 Gene names

Pitpnm1 Nir2 Pitpnm

Organism

Rattus norvegicus (Rat)

Nir2 Entry name

PITM1_RAT

Nir2 Codon optimized cDNA(gene) Clone

Nir2 Cat #

RPY2406

Tag

Nir2 contains A 6x histidine tag

Nir2 Formulation

Liquid

Nir2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Nir2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Nir2 Protein

Nir2 Cat #

PY2406

Nir2 Source

recombinant

Nir2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Nir2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Nir2 Activity

N/A

Tag

Nir2 Contains A 6x histidine tag

Nir2 Formulation

Liquid

Nir2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Nir2 family

PtdIns transfer protein family, PI transfer class IIA subfamily

Nir2 Subcellular locations

Cytoplasm. Golgi apparatus > Golgi stack membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Lipid droplet. Cleavage furrow. Midbody.

Nir2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions (By similarity).

Nir2 Sequence

DDBJ

EMBL

GenBank

Nir2 3D structure

ModBase

Nir2 interaction

STRING

Nir2 Proteomic

PRIDE

Nir2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Nir2 Organism specific

CTD

MGI

Nir2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Nir2 Gene expression

Bgee

ArrayExpress

Genevestigator

Nir2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY