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Human Nephrin (aa 1-1241 )

NPHN Swiss Prot#

O60500

NPHN Protein names

Nephrin (Renal glomerulus-specific cell adhesion receptor)

NPHN Gene names

NPHS1 NPHN

Organism

Homo sapiens (Human)

NPHN Entry name

NPHN_HUMAN

NPHN Codon optimized cDNA(gene) Clone

NPHN Cat #

RPY2404

Tag

NPHN contains A 6x histidine tag

NPHN Formulation

Liquid

NPHN Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NPHN Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NPHN Protein

NPHN Cat #

PY2404

NPHN Source

recombinant

NPHN Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NPHN Purity

>90%, as determined by SDS-PAGE under reducing conditions

NPHN Activity

N/A

Tag

NPHN Contains A 6x histidine tag

NPHN Formulation

Liquid

NPHN Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NPHN family

Immunoglobulin superfamily

NPHN Subcellular locations

Cell membrane; Single-pass type I membrane protein.

NPHN FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity).

NPHN Sequence

DDBJ

EMBL

GenBank

NPHN 3D structure

ModBase

NPHN interaction

STRING

NPHN Proteomic

PRIDE

NPHN Genome annotation

Ensembl

GeneID

KEGG

UCSC

NPHN Organism specific

CTD

MGI

NPHN Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NPHN Gene expression

Bgee

ArrayExpress

Genevestigator

NPHN Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY