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Human Nitric oxide synthase endothelial (aa 1-1203 )

NOS3 Swiss Prot#

P29474

NOS3 Protein names

Nitric oxide synthase, endothelial (EC 1.14.13.39) (Constitutive NOS) (cNOS) (EC-NOS) (Endothelial NOS) (eNOS) (NOS type III) (NOSIII)

NOS3 Gene names

NOS3

Organism

Homo sapiens (Human)

NOS3 Entry name

NOS3_HUMAN

NOS3 Codon optimized cDNA(gene) Clone

NOS3 Cat #

RPY2391

Tag

NOS3 contains A 6x histidine tag

NOS3 Formulation

Liquid

NOS3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NOS3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NOS3 Protein

NOS3 Cat #

PY2391

NOS3 Source

recombinant

NOS3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NOS3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

NOS3 Activity

N/A

Tag

NOS3 Contains A 6x histidine tag

NOS3 Formulation

Liquid

NOS3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NOS3 family

NOS family

NOS3 Subcellular locations

Cell membrane. Membrane > caveola. Cytoplasm > cytoskeleton. Golgi apparatus.

NOS3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

NOS3 Sequence

DDBJ

EMBL

GenBank

NOS3 3D structure

ModBase

NOS3 interaction

STRING

NOS3 Proteomic

PRIDE

NOS3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

NOS3 Organism specific

CTD

MGI

NOS3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NOS3 Gene expression

Bgee

ArrayExpress

Genevestigator

NOS3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY