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| Rat Arf-GAP SH3 domain ANK repeat PH domain-containing 1 (aa 1-1144 ) |
| Ddef1 Swiss Prot# | | Q1AAU6 |
| Ddef1 Protein names | | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP) |
| Ddef1 Gene names | | Asap1 Ddef1 |
| Organism | | Rattus norvegicus (Rat) |
| Ddef1 Entry name | | ASAP1_RAT |
| Ddef1 Codon optimized cDNA(gene) Clone |
| Ddef1 Cat # | | RPY2358 |
| Tag | | Ddef1 contains A 6x histidine tag |
| Ddef1 Formulation | | Liquid |
| Ddef1 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Ddef1 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Ddef1 Protein |
| Ddef1 Cat # | | PY2358 |
| Ddef1 Source | | recombinant |
| Ddef1 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Ddef1 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Ddef1 Activity | | N/A |
| Tag | | Ddef1 Contains A 6x histidine tag |
| Ddef1 Formulation | | Liquid |
| Ddef1 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Ddef1 Products | | For pricing and availability Click Here >>> |
| Ddef1 family | | - |
| Ddef1 Subcellular locations | | Cytoplasm. Membrane. |
| Ddef1 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Possesses phosphatidylinositol 4,5-biphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity). |
| Ddef1 Sequence | | DDBJ | EMBL | GenBank |
| Ddef1 3D structure | | ModBase |
| Ddef1 interaction | | STRING |
| Ddef1 Proteomic | | PRIDE |
| Ddef1 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Ddef1 Organism specific | | CTD | MGI |
| Ddef1 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Ddef1 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Ddef1 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |