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Human Huntingtin-interacting protein 1-related protein (aa 1-1068 )

HIP12 Swiss Prot#

O75146

HIP12 Protein names

Huntingtin-interacting protein 1-related protein (HIP1-related protein) (Huntingtin-interacting protein 12) (HIP-12)

HIP12 Gene names

HIP1R HIP12 KIAA0655

Organism

Homo sapiens (Human)

HIP12 Entry name

HIP1R_HUMAN

HIP12 Codon optimized cDNA(gene) Clone

HIP12 Cat #

RPY2298

Tag

HIP12 contains A 6x histidine tag

HIP12 Formulation

Liquid

HIP12 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

HIP12 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant HIP12 Protein

HIP12 Cat #

PY2298

HIP12 Source

recombinant

HIP12 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

HIP12 Purity

>90%, as determined by SDS-PAGE under reducing conditions

HIP12 Activity

N/A

Tag

HIP12 Contains A 6x histidine tag

HIP12 Formulation

Liquid

HIP12 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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HIP12 family

SLA2 family

HIP12 Subcellular locations

Cytoplasm > perinuclear region. Endomembrane system. Cytoplasmic vesicle > clathrin-coated vesicle membrane.

HIP12 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.

HIP12 Sequence

DDBJ

EMBL

GenBank

HIP12 3D structure

ModBase

HIP12 interaction

STRING

HIP12 Proteomic

PRIDE

HIP12 Genome annotation

Ensembl

GeneID

KEGG

UCSC

HIP12 Organism specific

CTD

MGI

HIP12 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

HIP12 Gene expression

Bgee

ArrayExpress

Genevestigator

HIP12 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY