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Mouse Vinculin (aa 1-1066 )

Vcl Swiss Prot#

Q64727

Vcl Protein names

Vinculin (Metavinculin)

Vcl Gene names

Vcl

Organism

Mus musculus (Mouse)

Vcl Entry name

VINC_MOUSE

Vcl Codon optimized cDNA(gene) Clone

Vcl Cat #

RPY2293

Tag

Vcl contains A 6x histidine tag

Vcl Formulation

Liquid

Vcl Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Vcl Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Vcl Protein

Vcl Cat #

PY2293

Vcl Source

recombinant

Vcl Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Vcl Purity

>90%, as determined by SDS-PAGE under reducing conditions

Vcl Activity

N/A

Tag

Vcl Contains A 6x histidine tag

Vcl Formulation

Liquid

Vcl Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Vcl family

Vinculin/alpha-catenin family

Vcl Subcellular locations

Cytoplasm > cytoskeleton. Cell junction > adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction.

Vcl FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion (By similarity).

Vcl Sequence

DDBJ

EMBL

GenBank

Vcl 3D structure

ModBase

Vcl interaction

STRING

Vcl Proteomic

PRIDE

Vcl Genome annotation

Ensembl

GeneID

KEGG

UCSC

Vcl Organism specific

CTD

MGI

Vcl Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Vcl Gene expression

Bgee

ArrayExpress

Genevestigator

Vcl Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY