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Human Myosin-Ic (aa 1-1063 )
MYO1C Swiss Prot#
O00159
MYO1C Protein names
Myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
MYO1C Gene names
MYO1C
Organism
Homo sapiens (Human)
MYO1C Entry name
MYO1C_HUMAN
MYO1C Codon optimized cDNA(gene) Clone
MYO1C Cat #
RPY2287
Tag
MYO1C contains A 6x histidine tag
MYO1C Formulation
Liquid
MYO1C Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
MYO1C Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant MYO1C Protein
MYO1C Cat #
PY2287
MYO1C Source
recombinant
MYO1C Applications
Western Blot, SDS-Page or may be used for other applications determined by user
MYO1C Purity
>90%, as determined by SDS-PAGE under reducing conditions
MYO1C Activity
N/A
Tag
MYO1C Contains A 6x histidine tag
MYO1C Formulation
Liquid
MYO1C Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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MYO1C family
-
MYO1C Subcellular locations
Cytoplasm. Cell membrane. Cell projection > stereocilium membrane. Nucleus > nucleoplasm. Nucleus > nucleolus. Nucleus > nuclear pore complex.
MYO1C FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells. Binds phosphoinositides and links the actin cytoskeleton to cellular membranes (By similarity).; FUNCTION: Isoform 3 is involved in regulation of transcription. Associated with transcriptional active ribosomal genes. Appears to cooperate with the WICH chromatin-remodeling complex to facilitate transcription. Necessary for the formation of the first phosphodiester bond during transcription initiation (By similarity).
MYO1C Sequence
DDBJ EMBL GenBank
MYO1C 3D structure
ModBase
MYO1C interaction
STRING
MYO1C Proteomic
PRIDE
MYO1C Genome annotation
Ensembl GeneID KEGG UCSC
MYO1C Organism specific
CTD MGI
MYO1C Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
MYO1C Gene expression
Bgee ArrayExpress Genevestigator
MYO1C Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY