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Mouse Inversin (aa 1-1062 )

Inv Swiss Prot#

O89019

Inv Protein names

Inversin (Inversion of embryo turning protein) (Nephrocystin-2)

Inv Gene names

Invs Inv Nphp2

Organism

Mus musculus (Mouse)

Inv Entry name

INVS_MOUSE

Inv Codon optimized cDNA(gene) Clone

Inv Cat #

RPY2286

Tag

Inv contains A 6x histidine tag

Inv Formulation

Liquid

Inv Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Inv Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Inv Protein

Inv Cat #

PY2286

Inv Source

recombinant

Inv Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Inv Purity

>90%, as determined by SDS-PAGE under reducing conditions

Inv Activity

N/A

Tag

Inv Contains A 6x histidine tag

Inv Formulation

Liquid

Inv Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Place Order for Recombinant Inv Products

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Inv family

-

Inv Subcellular locations

Cytoplasm. Cytoplasm > cytoskeleton. Membrane; Peripheral membrane protein. Nucleus. Cytoplasm > perinuclear region. Cytoplasm > cytoskeleton > spindle.

Inv FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling (By similarity).

Inv Sequence

DDBJ

EMBL

GenBank

Inv 3D structure

ModBase

Inv interaction

STRING

Inv Proteomic

PRIDE

Inv Genome annotation

Ensembl

GeneID

KEGG

UCSC

Inv Organism specific

CTD

MGI

Inv Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Inv Gene expression

Bgee

ArrayExpress

Genevestigator

Inv Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY