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Rat Meckelin (aa 1-992 )

Mks3 Swiss Prot#

P0C152

Mks3 Protein names

Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67)

Mks3 Gene names

Tmem67 Mks3 Wpk

Organism

Rattus norvegicus (Rat)

Mks3 Entry name

MKS3_RAT

Mks3 Codon optimized cDNA(gene) Clone

Mks3 Cat #

RPY2217

Tag

Mks3 contains A 6x histidine tag

Mks3 Formulation

Liquid

Mks3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Mks3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Mks3 Protein

Mks3 Cat #

PY2217

Mks3 Source

recombinant

Mks3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Mks3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Mks3 Activity

N/A

Tag

Mks3 Contains A 6x histidine tag

Mks3 Formulation

Liquid

Mks3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Mks3 family

-

Mks3 Subcellular locations

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm > cytoskeleton > cilium basal body.

Mks3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. Essential for endoplasmic deticulum-associated degradation (ERAD) of surfactant protein C (sftpc) (By similarity).

Mks3 Sequence

DDBJ

EMBL

GenBank

Mks3 3D structure

ModBase

Mks3 interaction

STRING

Mks3 Proteomic

PRIDE

Mks3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Mks3 Organism specific

CTD

MGI

Mks3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Mks3 Gene expression

Bgee

ArrayExpress

Genevestigator

Mks3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY