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Human Nesprin-3 (aa 1-975 )

C14orf49 Swiss Prot#

Q6ZMZ3

C14orf49 Protein names

Nesprin-3

C14orf49 Gene names

C14orf49

Organism

Homo sapiens (Human)

C14orf49 Entry name

SYNE3_HUMAN

C14orf49 Codon optimized cDNA(gene) Clone

C14orf49 Cat #

RPY2185

Tag

C14orf49 contains A 6x histidine tag

C14orf49 Formulation

Liquid

C14orf49 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

C14orf49 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant C14orf49 Protein

C14orf49 Cat #

PY2185

C14orf49 Source

recombinant

C14orf49 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

C14orf49 Purity

>90%, as determined by SDS-PAGE under reducing conditions

C14orf49 Activity

N/A

Tag

C14orf49 Contains A 6x histidine tag

C14orf49 Formulation

Liquid

C14orf49 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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C14orf49 family

Nesprin family

C14orf49 Subcellular locations

Nucleus outer membrane; Single-pass type IV membrane protein.

C14orf49 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.

C14orf49 Sequence

DDBJ

EMBL

GenBank

C14orf49 3D structure

ModBase

C14orf49 interaction

STRING

C14orf49 Proteomic

PRIDE

C14orf49 Genome annotation

Ensembl

GeneID

KEGG

UCSC

C14orf49 Organism specific

CTD

MGI

C14orf49 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

C14orf49 Gene expression

Bgee

ArrayExpress

Genevestigator

C14orf49 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY