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Mouse Phosphatidate phosphatase LPIN1 (aa 1-924 )

Fld Swiss Prot#

Q91ZP3

Fld Protein names

Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Fatty liver dystrophy protein) (Lipin-1)

Fld Gene names

Lpin1 Fld

Organism

Mus musculus (Mouse)

Fld Entry name

LPIN1_MOUSE

Fld Codon optimized cDNA(gene) Clone

Fld Cat #

RPY2129

Tag

Fld contains A 6x histidine tag

Fld Formulation

Liquid

Fld Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Fld Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Fld Protein

Fld Cat #

PY2129

Fld Source

recombinant

Fld Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Fld Purity

>90%, as determined by SDS-PAGE under reducing conditions

Fld Activity

N/A

Tag

Fld Contains A 6x histidine tag

Fld Formulation

Liquid

Fld Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Fld family

Lipin family

Fld Subcellular locations

Nucleus. Cytoplasm. Endoplasmic reticulum membrane.

Fld FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation.

Fld Sequence

DDBJ

EMBL

GenBank

Fld 3D structure

ModBase

Fld interaction

STRING

Fld Proteomic

PRIDE

Fld Genome annotation

Ensembl

GeneID

KEGG

UCSC

Fld Organism specific

CTD

MGI

Fld Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Fld Gene expression

Bgee

ArrayExpress

Genevestigator

Fld Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY