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Human Inner centromere protein (aa 1-918 )

INCENP Swiss Prot#

Q9NQS7

INCENP Protein names

Inner centromere protein

INCENP Gene names

INCENP

Organism

Homo sapiens (Human)

INCENP Entry name

INCE_HUMAN

INCENP Codon optimized cDNA(gene) Clone

INCENP Cat #

RPY2120

Tag

INCENP contains A 6x histidine tag

INCENP Formulation

Liquid

INCENP Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

INCENP Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant INCENP Protein

INCENP Cat #

PY2120

INCENP Source

recombinant

INCENP Applications

Western Blot, SDS-Page or may be used for other applications determined by user

INCENP Purity

>90%, as determined by SDS-PAGE under reducing conditions

INCENP Activity

N/A

Tag

INCENP Contains A 6x histidine tag

INCENP Formulation

Liquid

INCENP Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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INCENP family

INCENP family

INCENP Subcellular locations

Chromosome > centromere. Cytoplasm > cytoskeleton > spindle. Nucleus. Chromosome > centromere > kinetochore.

INCENP FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Probably acts through association with AURKB or AURKC. Seems to bind directly to microtubules. Controls the kinetochore localization of BUB1.

INCENP Sequence

DDBJ

EMBL

GenBank

INCENP 3D structure

ModBase

INCENP interaction

STRING

INCENP Proteomic

PRIDE

INCENP Genome annotation

Ensembl

GeneID

KEGG

UCSC

INCENP Organism specific

CTD

MGI

INCENP Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

INCENP Gene expression

Bgee

ArrayExpress

Genevestigator

INCENP Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY