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Mouse SUN domain-containing protein 1 (aa 1-913 )

Unc84a Swiss Prot#

Q9D666

Unc84a Protein names

SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1)

Unc84a Gene names

Sun1 Unc84a

Organism

Mus musculus (Mouse)

Unc84a Entry name

SUN1_MOUSE

Unc84a Codon optimized cDNA(gene) Clone

Unc84a Cat #

RPY2117

Tag

Unc84a contains A 6x histidine tag

Unc84a Formulation

Liquid

Unc84a Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Unc84a Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Unc84a Protein

Unc84a Cat #

PY2117

Unc84a Source

recombinant

Unc84a Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Unc84a Purity

>90%, as determined by SDS-PAGE under reducing conditions

Unc84a Activity

N/A

Tag

Unc84a Contains A 6x histidine tag

Unc84a Formulation

Liquid

Unc84a Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Unc84a family

-

Unc84a Subcellular locations

Nucleus inner membrane; Single-pass type II membrane protein.

Unc84a FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs).

Unc84a Sequence

DDBJ

EMBL

GenBank

Unc84a 3D structure

ModBase

Unc84a interaction

STRING

Unc84a Proteomic

PRIDE

Unc84a Genome annotation

Ensembl

GeneID

KEGG

UCSC

Unc84a Organism specific

CTD

MGI

Unc84a Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Unc84a Gene expression

Bgee

ArrayExpress

Genevestigator

Unc84a Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY