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Human Disks large homolog 1 (aa 1-904 )

DLG1 Swiss Prot#

Q12959

DLG1 Protein names

Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)

DLG1 Gene names

DLG1

Organism

Homo sapiens (Human)

DLG1 Entry name

DLG1_HUMAN

DLG1 Codon optimized cDNA(gene) Clone

DLG1 Cat #

RPY2097

Tag

DLG1 contains A 6x histidine tag

DLG1 Formulation

Liquid

DLG1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

DLG1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant DLG1 Protein

DLG1 Cat #

PY2097

DLG1 Source

recombinant

DLG1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

DLG1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

DLG1 Activity

N/A

Tag

DLG1 Contains A 6x histidine tag

DLG1 Formulation

Liquid

DLG1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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DLG1 family

MAGUK family

DLG1 Subcellular locations

Membrane; Peripheral membrane protein. Basolateral cell membrane. Endoplasmic reticulum membrane. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Cell membrane > sarcolemma.

DLG1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel.

DLG1 Sequence

DDBJ

EMBL

GenBank

DLG1 3D structure

ModBase

DLG1 interaction

STRING

DLG1 Proteomic

PRIDE

DLG1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

DLG1 Organism specific

CTD

MGI

DLG1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

DLG1 Gene expression

Bgee

ArrayExpress

Genevestigator

DLG1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY