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Mouse Dystroglycan (aa 1-893 )

Dag-1 Swiss Prot#

Q62165

Dag-1 Protein names

Dystroglycan (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)]

Dag-1 Gene names

Dag1 Dag-1

Organism

Mus musculus (Mouse)

Dag-1 Entry name

DAG1_MOUSE

Dag-1 Codon optimized cDNA(gene) Clone

Dag-1 Cat #

RPY2083

Tag

Dag-1 contains A 6x histidine tag

Dag-1 Formulation

Liquid

Dag-1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Dag-1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Dag-1 Protein

Dag-1 Cat #

PY2083

Dag-1 Source

recombinant

Dag-1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Dag-1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Dag-1 Activity

N/A

Tag

Dag-1 Contains A 6x histidine tag

Dag-1 Formulation

Liquid

Dag-1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Dag-1 family

-

Dag-1 Subcellular locations

Secreted > extracellular space. Cell membrane; Single-pass type I membrane protein. Cytoplasm > cytoskeleton. Nucleus > nucleoplasm.

Dag-1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.; FUNCTION: Alpha-dystroglycan is an extracellular peripheral glycoprotein that acts as a receptor for both extracellular matrix proteins containing laminin-G domains, and for certain adenoviruses. Receptor for laminin-2 (LAMA2) and agrin in peripheral nerve Schwann cells. Also receptor for lymphocytic choriomeningitis virus, Old World Lassa fever virus, and clade C New World arenaviruses.; FUNCTION: Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity (By similarity).

Dag-1 Sequence

DDBJ

EMBL

GenBank

Dag-1 3D structure

ModBase

Dag-1 interaction

STRING

Dag-1 Proteomic

PRIDE

Dag-1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Dag-1 Organism specific

CTD

MGI

Dag-1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Dag-1 Gene expression

Bgee

ArrayExpress

Genevestigator

Dag-1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY