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Human Integrator complex subunit 6 (aa 1-887 )

DBI1 Swiss Prot#

Q9UL03

DBI1 Protein names

Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1)

DBI1 Gene names

INTS6 DBI1 DDX26 DDX26A

Organism

Homo sapiens (Human)

DBI1 Entry name

INT6_HUMAN

DBI1 Codon optimized cDNA(gene) Clone

DBI1 Cat #

RPY2072

Tag

DBI1 contains A 6x histidine tag

DBI1 Formulation

Liquid

DBI1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

DBI1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant DBI1 Protein

DBI1 Cat #

PY2072

DBI1 Source

recombinant

DBI1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

DBI1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

DBI1 Activity

N/A

Tag

DBI1 Contains A 6x histidine tag

DBI1 Formulation

Liquid

DBI1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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DBI1 family

Integrator subunit 6 family

DBI1 Subcellular locations

Nucleus.

DBI1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.

DBI1 Sequence

DDBJ

EMBL

GenBank

DBI1 3D structure

ModBase

DBI1 interaction

STRING

DBI1 Proteomic

PRIDE

DBI1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

DBI1 Organism specific

CTD

MGI

DBI1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

DBI1 Gene expression

Bgee

ArrayExpress

Genevestigator

DBI1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY