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Human Breast cancer anti-estrogen resistance protein 1 (aa 1-870 )

CAS Swiss Prot#

P56945

CAS Protein names

Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)

CAS Gene names

BCAR1 CAS CASS1 CRKAS

Organism

Homo sapiens (Human)

CAS Entry name

BCAR1_HUMAN

CAS Codon optimized cDNA(gene) Clone

CAS Cat #

RPY2049

Tag

CAS contains A 6x histidine tag

CAS Formulation

Liquid

CAS Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CAS Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CAS Protein

CAS Cat #

PY2049

CAS Source

recombinant

CAS Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CAS Purity

>90%, as determined by SDS-PAGE under reducing conditions

CAS Activity

N/A

Tag

CAS Contains A 6x histidine tag

CAS Formulation

Liquid

CAS Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CAS family

CAS family

CAS Subcellular locations

Cell junction > focal adhesion. Cytoplasm.

CAS FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.

CAS Sequence

DDBJ

EMBL

GenBank

CAS 3D structure

ModBase

CAS interaction

STRING

CAS Proteomic

PRIDE

CAS Genome annotation

Ensembl

GeneID

KEGG

UCSC

CAS Organism specific

CTD

MGI

CAS Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CAS Gene expression

Bgee

ArrayExpress

Genevestigator

CAS Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY