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Mouse Protein monoglycylase TTLL8 (aa 1-832 )

Ttll8 Swiss Prot#

A4Q9F1

Ttll8 Protein names

Protein monoglycylase TTLL8 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 8)

Ttll8 Gene names

Ttll8

Organism

Mus musculus (Mouse)

Ttll8 Entry name

TTLL8_MOUSE

Ttll8 Codon optimized cDNA(gene) Clone

Ttll8 Cat #

RPY1989

Tag

Ttll8 contains A 6x histidine tag

Ttll8 Formulation

Liquid

Ttll8 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Ttll8 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Ttll8 Protein

Ttll8 Cat #

PY1989

Ttll8 Source

recombinant

Ttll8 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Ttll8 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Ttll8 Activity

N/A

Tag

Ttll8 Contains A 6x histidine tag

Ttll8 Formulation

Liquid

Ttll8 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Ttll8 family

-

Ttll8 Subcellular locations

Cytoplasm > cytoskeleton. Cell projection > cilium. Cytoplasm > cytoskeleton > cilium axoneme.

Ttll8 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction.

Ttll8 Sequence

DDBJ

EMBL

GenBank

Ttll8 3D structure

ModBase

Ttll8 interaction

STRING

Ttll8 Proteomic

PRIDE

Ttll8 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Ttll8 Organism specific

CTD

MGI

Ttll8 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Ttll8 Gene expression

Bgee

ArrayExpress

Genevestigator

Ttll8 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY