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Mouse Serine threonine-protein phosphatase 4 3A (aa 1-820 )

Smek1 Swiss Prot#

Q6P2K6

Smek1 Protein names

Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1)

Smek1 Gene names

Smek1 Kiaa2010 Pp4r3a Ppp4r3a

Organism

Mus musculus (Mouse)

Smek1 Entry name

P4R3A_MOUSE

Smek1 Codon optimized cDNA(gene) Clone

Smek1 Cat #

RPY1966

Tag

Smek1 contains A 6x histidine tag

Smek1 Formulation

Liquid

Smek1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Smek1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Smek1 Protein

Smek1 Cat #

PY1966

Smek1 Source

recombinant

Smek1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Smek1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Smek1 Activity

N/A

Tag

Smek1 Contains A 6x histidine tag

Smek1 Formulation

Liquid

Smek1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Smek1 family

SMEK family

Smek1 Subcellular locations

Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Nucleus.

Smek1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair (By similarity).

Smek1 Sequence

DDBJ

EMBL

GenBank

Smek1 3D structure

ModBase

Smek1 interaction

STRING

Smek1 Proteomic

PRIDE

Smek1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Smek1 Organism specific

CTD

MGI

Smek1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Smek1 Gene expression

Bgee

ArrayExpress

Genevestigator

Smek1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY