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Human SUN domain-containing protein 1 (aa 1-812 )

SUN1 Swiss Prot#

O94901

SUN1 Protein names

SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1)

SUN1 Gene names

SUN1 KIAA0810 UNC84A

Organism

Homo sapiens (Human)

SUN1 Entry name

SUN1_HUMAN

SUN1 Codon optimized cDNA(gene) Clone

SUN1 Cat #

RPY1948

Tag

SUN1 contains A 6x histidine tag

SUN1 Formulation

Liquid

SUN1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SUN1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SUN1 Protein

SUN1 Cat #

PY1948

SUN1 Source

recombinant

SUN1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SUN1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

SUN1 Activity

N/A

Tag

SUN1 Contains A 6x histidine tag

SUN1 Formulation

Liquid

SUN1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SUN1 family

-

SUN1 Subcellular locations

Nucleus inner membrane; Single-pass type II membrane protein.

SUN1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs) (By similarity).

SUN1 Sequence

DDBJ

EMBL

GenBank

SUN1 3D structure

ModBase

SUN1 interaction

STRING

SUN1 Proteomic

PRIDE

SUN1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

SUN1 Organism specific

CTD

MGI

SUN1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SUN1 Gene expression

Bgee

ArrayExpress

Genevestigator

SUN1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY