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Human Caldesmon (aa 1-793 )

CAD Swiss Prot#

Q05682

CAD Protein names

Caldesmon (CDM)

CAD Gene names

CALD1 CAD CDM

Organism

Homo sapiens (Human)

CAD Entry name

CALD1_HUMAN

CAD Codon optimized cDNA(gene) Clone

CAD Cat #

RPY1922

Tag

CAD contains A 6x histidine tag

CAD Formulation

Liquid

CAD Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CAD Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CAD Protein

CAD Cat #

PY1922

CAD Source

recombinant

CAD Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CAD Purity

>90%, as determined by SDS-PAGE under reducing conditions

CAD Activity

N/A

Tag

CAD Contains A 6x histidine tag

CAD Formulation

Liquid

CAD Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CAD family

Caldesmon family

CAD Subcellular locations

Cytoplasm > cytoskeleton. Cytoplasm > myofibril.

CAD FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping.

CAD Sequence

DDBJ

EMBL

GenBank

CAD 3D structure

ModBase

CAD interaction

STRING

CAD Proteomic

PRIDE

CAD Genome annotation

Ensembl

GeneID

KEGG

UCSC

CAD Organism specific

CTD

MGI

CAD Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CAD Gene expression

Bgee

ArrayExpress

Genevestigator

CAD Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY