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| Human Pleckstrin homology domain-containing family G 6 (aa 1-790 ) |
| PLEKHG6 Swiss Prot# | | Q3KR16 |
| PLEKHG6 Protein names | | Pleckstrin homology domain-containing family G member 6 (PH domain-containing family G member 6) (Myosin-interacting guanine nucleotide exchange factor) (MyoGEF) |
| PLEKHG6 Gene names | | PLEKHG6 |
| Organism | | Homo sapiens (Human) |
| PLEKHG6 Entry name | | PKHG6_HUMAN |
| PLEKHG6 Codon optimized cDNA(gene) Clone |
| PLEKHG6 Cat # | | RPY1917 |
| Tag | | PLEKHG6 contains A 6x histidine tag |
| PLEKHG6 Formulation | | Liquid |
| PLEKHG6 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| PLEKHG6 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant PLEKHG6 Protein |
| PLEKHG6 Cat # | | PY1917 |
| PLEKHG6 Source | | recombinant |
| PLEKHG6 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| PLEKHG6 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| PLEKHG6 Activity | | N/A |
| Tag | | PLEKHG6 Contains A 6x histidine tag |
| PLEKHG6 Formulation | | Liquid |
| PLEKHG6 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant PLEKHG6 Products | | For pricing and availability Click Here >>> |
| PLEKHG6 family | | - |
| PLEKHG6 Subcellular locations | | Cytoplasm. Cytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole. Cleavage furrow. |
| PLEKHG6 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis. |
| PLEKHG6 Sequence | | DDBJ | EMBL | GenBank |
| PLEKHG6 3D structure | | ModBase |
| PLEKHG6 interaction | | STRING |
| PLEKHG6 Proteomic | | PRIDE |
| PLEKHG6 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| PLEKHG6 Organism specific | | CTD | MGI |
| PLEKHG6 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| PLEKHG6 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| PLEKHG6 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |