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Mouse Rho GTPase-activating protein 10 (aa 1-786 )

Arhgap10 Swiss Prot#

Q6Y5D8

Arhgap10 Protein names

Rho GTPase-activating protein 10 (PH and SH3 domain-containing rhoGAP protein) (PS-GAP) (PSGAP) (Rho-type GTPase-activating protein 10)

Arhgap10 Gene names

Arhgap10

Organism

Mus musculus (Mouse)

Arhgap10 Entry name

RHG10_MOUSE

Arhgap10 Codon optimized cDNA(gene) Clone

Arhgap10 Cat #

RPY1914

Tag

Arhgap10 contains A 6x histidine tag

Arhgap10 Formulation

Liquid

Arhgap10 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Arhgap10 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Arhgap10 Protein

Arhgap10 Cat #

PY1914

Arhgap10 Source

recombinant

Arhgap10 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Arhgap10 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Arhgap10 Activity

N/A

Tag

Arhgap10 Contains A 6x histidine tag

Arhgap10 Formulation

Liquid

Arhgap10 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Arhgap10 family

-

Arhgap10 Subcellular locations

Cytoplasm. Cytoplasm > perinuclear region. Cell membrane.

Arhgap10 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.

Arhgap10 Sequence

DDBJ

EMBL

GenBank

Arhgap10 3D structure

ModBase

Arhgap10 interaction

STRING

Arhgap10 Proteomic

PRIDE

Arhgap10 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Arhgap10 Organism specific

CTD

MGI

Arhgap10 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Arhgap10 Gene expression

Bgee

ArrayExpress

Genevestigator

Arhgap10 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY