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Human FYVE RhoGEF PH domain-containing protein 4 (aa 1-766 )

FRABP Swiss Prot#

Q96M96

FRABP Protein names

FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6)

FRABP Gene names

FGD4 FRABP ZFYVE6

Organism

Homo sapiens (Human)

FRABP Entry name

FGD4_HUMAN

FRABP Codon optimized cDNA(gene) Clone

FRABP Cat #

RPY1874

Tag

FRABP contains A 6x histidine tag

FRABP Formulation

Liquid

FRABP Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

FRABP Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant FRABP Protein

FRABP Cat #

PY1874

FRABP Source

recombinant

FRABP Applications

Western Blot, SDS-Page or may be used for other applications determined by user

FRABP Purity

>90%, as determined by SDS-PAGE under reducing conditions

FRABP Activity

N/A

Tag

FRABP Contains A 6x histidine tag

FRABP Formulation

Liquid

FRABP Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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FRABP family

-

FRABP Subcellular locations

Cytoplasm > cytoskeleton. Cell projection > filopodium.

FRABP FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8 (By similarity).

FRABP Sequence

DDBJ

EMBL

GenBank

FRABP 3D structure

ModBase

FRABP interaction

STRING

FRABP Proteomic

PRIDE

FRABP Genome annotation

Ensembl

GeneID

KEGG

UCSC

FRABP Organism specific

CTD

MGI

FRABP Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

FRABP Gene expression

Bgee

ArrayExpress

Genevestigator

FRABP Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY