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Rat Mit usin-2 (aa 1-757 )

Fzo1a Swiss Prot#

Q8R500

Fzo1a Protein names

Mitofusin-2 (EC 3.6.5.-) (Mitochondrial transmembrane GTPase FZO1A) (Protein HSG) (Transmembrane GTPase MFN2)

Fzo1a Gene names

Mfn2 Fzo1a

Organism

Rattus norvegicus (Rat)

Fzo1a Entry name

MFN2_RAT

Fzo1a Codon optimized cDNA(gene) Clone

Fzo1a Cat #

RPY1867

Tag

Fzo1a contains A 6x histidine tag

Fzo1a Formulation

Liquid

Fzo1a Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Fzo1a Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Fzo1a Protein

Fzo1a Cat #

PY1867

Fzo1a Source

recombinant

Fzo1a Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Fzo1a Purity

>90%, as determined by SDS-PAGE under reducing conditions

Fzo1a Activity

N/A

Tag

Fzo1a Contains A 6x histidine tag

Fzo1a Formulation

Liquid

Fzo1a Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Fzo1a family

Mitofusin family

Fzo1a Subcellular locations

Mitochondrion outer membrane; Multi-pass membrane protein.

Fzo1a FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation.

Fzo1a Sequence

DDBJ

EMBL

GenBank

Fzo1a 3D structure

ModBase

Fzo1a interaction

STRING

Fzo1a Proteomic

PRIDE

Fzo1a Genome annotation

Ensembl

GeneID

KEGG

UCSC

Fzo1a Organism specific

CTD

MGI

Fzo1a Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Fzo1a Gene expression

Bgee

ArrayExpress

Genevestigator

Fzo1a Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY