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Mouse Mit usin-2 (aa 1-757 )

Mfn2 Swiss Prot#

Q80U63

Mfn2 Protein names

Mitofusin-2 (EC 3.6.5.-) (Hypertension-related protein 1) (Mitochondrial assembly regulatory factor) (HSG protein) (Transmembrane GTPase MFN2)

Mfn2 Gene names

Mfn2 Kiaa0214 Marf

Organism

Mus musculus (Mouse)

Mfn2 Entry name

MFN2_MOUSE

Mfn2 Codon optimized cDNA(gene) Clone

Mfn2 Cat #

RPY1865

Tag

Mfn2 contains A 6x histidine tag

Mfn2 Formulation

Liquid

Mfn2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Mfn2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Mfn2 Protein

Mfn2 Cat #

PY1865

Mfn2 Source

recombinant

Mfn2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Mfn2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Mfn2 Activity

N/A

Tag

Mfn2 Contains A 6x histidine tag

Mfn2 Formulation

Liquid

Mfn2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Mfn2 family

Mitofusin family

Mfn2 Subcellular locations

Mitochondrion outer membrane; Multi-pass membrane protein.

Mfn2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation.

Mfn2 Sequence

DDBJ

EMBL

GenBank

Mfn2 3D structure

ModBase

Mfn2 interaction

STRING

Mfn2 Proteomic

PRIDE

Mfn2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Mfn2 Organism specific

CTD

MGI

Mfn2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Mfn2 Gene expression

Bgee

ArrayExpress

Genevestigator

Mfn2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY