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Human Mit usin-2 (aa 1-757 )

CPRP1 Swiss Prot#

O95140

CPRP1 Protein names

Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2)

CPRP1 Gene names

MFN2 CPRP1 KIAA0214

Organism

Homo sapiens (Human)

CPRP1 Entry name

MFN2_HUMAN

CPRP1 Codon optimized cDNA(gene) Clone

CPRP1 Cat #

RPY1863

Tag

CPRP1 contains A 6x histidine tag

CPRP1 Formulation

Liquid

CPRP1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CPRP1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CPRP1 Protein

CPRP1 Cat #

PY1863

CPRP1 Source

recombinant

CPRP1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CPRP1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CPRP1 Activity

N/A

Tag

CPRP1 Contains A 6x histidine tag

CPRP1 Formulation

Liquid

CPRP1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CPRP1 family

Mitofusin family

CPRP1 Subcellular locations

Mitochondrion outer membrane; Multi-pass membrane protein.

CPRP1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation.

CPRP1 Sequence

DDBJ

EMBL

GenBank

CPRP1 3D structure

ModBase

CPRP1 interaction

STRING

CPRP1 Proteomic

PRIDE

CPRP1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CPRP1 Organism specific

CTD

MGI

CPRP1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CPRP1 Gene expression

Bgee

ArrayExpress

Genevestigator

CPRP1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY