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Mouse Rho GTPase-activating protein 24 (aa 1-747 )

Arhgap24 Swiss Prot#

Q8C4V1

Arhgap24 Protein names

Rho GTPase-activating protein 24 (Rho-type GTPase-activating protein 24)

Arhgap24 Gene names

Arhgap24

Organism

Mus musculus (Mouse)

Arhgap24 Entry name

RHG24_MOUSE

Arhgap24 Codon optimized cDNA(gene) Clone

Arhgap24 Cat #

RPY1848

Tag

Arhgap24 contains A 6x histidine tag

Arhgap24 Formulation

Liquid

Arhgap24 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Arhgap24 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Arhgap24 Protein

Arhgap24 Cat #

PY1848

Arhgap24 Source

recombinant

Arhgap24 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Arhgap24 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Arhgap24 Activity

N/A

Tag

Arhgap24 Contains A 6x histidine tag

Arhgap24 Formulation

Liquid

Arhgap24 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Arhgap24 family

-

Arhgap24 Subcellular locations

Cytoplasm > cytoskeleton. Cell junction > adherens junction. Cell junction > focal adhesion. Cell projection.

Arhgap24 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis (By similarity).

Arhgap24 Sequence

DDBJ

EMBL

GenBank

Arhgap24 3D structure

ModBase

Arhgap24 interaction

STRING

Arhgap24 Proteomic

PRIDE

Arhgap24 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Arhgap24 Organism specific

CTD

MGI

Arhgap24 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Arhgap24 Gene expression

Bgee

ArrayExpress

Genevestigator

Arhgap24 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY