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Human Targeting protein for Xklp2 (aa 1-747 )

C20orf1 Swiss Prot#

Q9ULW0

C20orf1 Protein names

Targeting protein for Xklp2 (Differentially expressed in cancerous and non-cancerous lung cells 2) (DIL-2) (Hepatocellular carcinoma-associated antigen 519) (Protein fls353) (Restricted expression proliferation-associated protein 100) (p100)

C20orf1 Gene names

TPX2 C20orf1 C20orf2 DIL2 HCA519

Organism

Homo sapiens (Human)

C20orf1 Entry name

TPX2_HUMAN

C20orf1 Codon optimized cDNA(gene) Clone

C20orf1 Cat #

RPY1844

Tag

C20orf1 contains A 6x histidine tag

C20orf1 Formulation

Liquid

C20orf1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

C20orf1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant C20orf1 Protein

C20orf1 Cat #

PY1844

C20orf1 Source

recombinant

C20orf1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

C20orf1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

C20orf1 Activity

N/A

Tag

C20orf1 Contains A 6x histidine tag

C20orf1 Formulation

Liquid

C20orf1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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C20orf1 family

TPX2 family

C20orf1 Subcellular locations

Nucleus. Cytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole.

C20orf1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.

C20orf1 Sequence

DDBJ

EMBL

GenBank

C20orf1 3D structure

ModBase

C20orf1 interaction

STRING

C20orf1 Proteomic

PRIDE

C20orf1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

C20orf1 Organism specific

CTD

MGI

C20orf1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

C20orf1 Gene expression

Bgee

ArrayExpress

Genevestigator

C20orf1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY