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Human Exostosin-1 (aa 1-746 )

EXT1 Swiss Prot#

Q16394

EXT1 Protein names

Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1) (Putative tumor suppressor protein EXT1)

EXT1 Gene names

EXT1

Organism

Homo sapiens (Human)

EXT1 Entry name

EXT1_HUMAN

EXT1 Codon optimized cDNA(gene) Clone

EXT1 Cat #

RPY1842

Tag

EXT1 contains A 6x histidine tag

EXT1 Formulation

Liquid

EXT1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

EXT1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant EXT1 Protein

EXT1 Cat #

PY1842

EXT1 Source

recombinant

EXT1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

EXT1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

EXT1 Activity

N/A

Tag

EXT1 Contains A 6x histidine tag

EXT1 Formulation

Liquid

EXT1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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EXT1 family

Glycosyltransferase 47 family

EXT1 Subcellular locations

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.

EXT1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor.

EXT1 Sequence

DDBJ

EMBL

GenBank

EXT1 3D structure

ModBase

EXT1 interaction

STRING

EXT1 Proteomic

PRIDE

EXT1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

EXT1 Organism specific

CTD

MGI

EXT1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

EXT1 Gene expression

Bgee

ArrayExpress

Genevestigator

EXT1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY