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Mouse Targeting protein for Xklp2 (aa 1-745 )

Tpx2 Swiss Prot#

A2APB8

Tpx2 Protein names

Targeting protein for Xklp2

Tpx2 Gene names

Tpx2

Organism

Mus musculus (Mouse)

Tpx2 Entry name

TPX2_MOUSE

Tpx2 Codon optimized cDNA(gene) Clone

Tpx2 Cat #

RPY1840

Tag

Tpx2 contains A 6x histidine tag

Tpx2 Formulation

Liquid

Tpx2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Tpx2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Tpx2 Protein

Tpx2 Cat #

PY1840

Tpx2 Source

recombinant

Tpx2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Tpx2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Tpx2 Activity

N/A

Tag

Tpx2 Contains A 6x histidine tag

Tpx2 Formulation

Liquid

Tpx2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Tpx2 family

TPX2 family

Tpx2 Subcellular locations

Nucleus. Cytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole.

Tpx2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation and protects the phosphorylated residue against dephosphorylation (By similarity).

Tpx2 Sequence

DDBJ

EMBL

GenBank

Tpx2 3D structure

ModBase

Tpx2 interaction

STRING

Tpx2 Proteomic

PRIDE

Tpx2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Tpx2 Organism specific

CTD

MGI

Tpx2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Tpx2 Gene expression

Bgee

ArrayExpress

Genevestigator

Tpx2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY