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Mouse Microtubule-associated protein tau (aa 1-733 )

Mtapt Swiss Prot#

P10637

Mtapt Protein names

Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)

Mtapt Gene names

Mapt Mtapt Tau

Organism

Mus musculus (Mouse)

Mtapt Entry name

TAU_MOUSE

Mtapt Codon optimized cDNA(gene) Clone

Mtapt Cat #

RPY1816

Tag

Mtapt contains A 6x histidine tag

Mtapt Formulation

Liquid

Mtapt Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Mtapt Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Mtapt Protein

Mtapt Cat #

PY1816

Mtapt Source

recombinant

Mtapt Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Mtapt Purity

>90%, as determined by SDS-PAGE under reducing conditions

Mtapt Activity

N/A

Tag

Mtapt Contains A 6x histidine tag

Mtapt Formulation

Liquid

Mtapt Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Mtapt family

-

Mtapt Subcellular locations

Cytoplasm > cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm > cytoskeleton. Cell projection > axon.

Mtapt FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Mtapt Sequence

DDBJ

EMBL

GenBank

Mtapt 3D structure

ModBase

Mtapt interaction

STRING

Mtapt Proteomic

PRIDE

Mtapt Genome annotation

Ensembl

GeneID

KEGG

UCSC

Mtapt Organism specific

CTD

MGI

Mtapt Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Mtapt Gene expression

Bgee

ArrayExpress

Genevestigator

Mtapt Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY