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Mouse SUN domain-containing protein 2 (aa 1-731 )
Unc84b Swiss Prot#
Q8BJS4
Unc84b Protein names
SUN domain-containing protein 2 (Protein unc-84 homolog B) (Sad1/unc-84 protein-like 2)
Unc84b Gene names
Sun2 Unc84b
Organism
Mus musculus (Mouse)
Unc84b Entry name
SUN2_MOUSE
Unc84b Codon optimized cDNA(gene) Clone
Unc84b Cat #
RPY1806
Tag
Unc84b contains A 6x histidine tag
Unc84b Formulation
Liquid
Unc84b Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Unc84b Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Unc84b Protein
Unc84b Cat #
PY1806
Unc84b Source
recombinant
Unc84b Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Unc84b Purity
>90%, as determined by SDS-PAGE under reducing conditions
Unc84b Activity
N/A
Tag
Unc84b Contains A 6x histidine tag
Unc84b Formulation
Liquid
Unc84b Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Unc84b family
-
Unc84b Subcellular locations
Nucleus inner membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Unc84b FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Specifically, Syne2 and Sun2 assemble in arrays of transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. May also function on endocytic vesicles as a receptor for Rab5-GDP and participate in the activation of Rab5.
Unc84b Sequence
DDBJ EMBL GenBank
Unc84b 3D structure
ModBase
Unc84b interaction
STRING
Unc84b Proteomic
PRIDE
Unc84b Genome annotation
Ensembl GeneID KEGG UCSC
Unc84b Organism specific
CTD MGI
Unc84b Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Unc84b Gene expression
Bgee ArrayExpress Genevestigator
Unc84b Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY