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| Mouse SUN domain-containing protein 2 (aa 1-731 ) |
| Unc84b Swiss Prot# | | Q8BJS4 |
| Unc84b Protein names | | SUN domain-containing protein 2 (Protein unc-84 homolog B) (Sad1/unc-84 protein-like 2) |
| Unc84b Gene names | | Sun2 Unc84b |
| Organism | | Mus musculus (Mouse) |
| Unc84b Entry name | | SUN2_MOUSE |
| Unc84b Codon optimized cDNA(gene) Clone |
| Unc84b Cat # | | RPY1806 |
| Tag | | Unc84b contains A 6x histidine tag |
| Unc84b Formulation | | Liquid |
| Unc84b Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Unc84b Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Unc84b Protein |
| Unc84b Cat # | | PY1806 |
| Unc84b Source | | recombinant |
| Unc84b Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Unc84b Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Unc84b Activity | | N/A |
| Tag | | Unc84b Contains A 6x histidine tag |
| Unc84b Formulation | | Liquid |
| Unc84b Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Unc84b Products | | For pricing and availability Click Here >>> |
| Unc84b family | | - |
| Unc84b Subcellular locations | | Nucleus inner membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. |
| Unc84b FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Specifically, Syne2 and Sun2 assemble in arrays of transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. May also function on endocytic vesicles as a receptor for Rab5-GDP and participate in the activation of Rab5. |
| Unc84b Sequence | | DDBJ | EMBL | GenBank |
| Unc84b 3D structure | | ModBase |
| Unc84b interaction | | STRING |
| Unc84b Proteomic | | PRIDE |
| Unc84b Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Unc84b Organism specific | | CTD | MGI |
| Unc84b Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Unc84b Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Unc84b Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |