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  • For cDNA or Recombinant Protein Search ( Input  
    Gene name, or Protein Name, or Swiss -prot Accession
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Human Actin filament-associated protein 1 (aa 1-730 )
AFAP Swiss Prot#
Q8N556
AFAP Protein names
Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110)
AFAP Gene names
AFAP1 AFAP
Organism
Homo sapiens (Human)
AFAP Entry name
AFAP1_HUMAN
AFAP Codon optimized cDNA(gene) Clone
AFAP Cat #
RPY1799
Tag
AFAP contains A 6x histidine tag
AFAP Formulation
Liquid
AFAP Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
AFAP Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant AFAP Protein
AFAP Cat #
PY1799
AFAP Source
recombinant
AFAP Applications
Western Blot, SDS-Page or may be used for other applications determined by user
AFAP Purity
>90%, as determined by SDS-PAGE under reducing conditions
AFAP Activity
N/A
Tag
AFAP Contains A 6x histidine tag
AFAP Formulation
Liquid
AFAP Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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AFAP family
-
AFAP Subcellular locations
Cytoplasm > cytoskeleton.
AFAP FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
AFAP Sequence
DDBJ EMBL GenBank
AFAP 3D structure
ModBase
AFAP interaction
STRING
AFAP Proteomic
PRIDE
AFAP Genome annotation
Ensembl GeneID KEGG UCSC
AFAP Organism specific
CTD MGI
AFAP Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
AFAP Gene expression
Bgee ArrayExpress Genevestigator
AFAP Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY