|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
||||||||||||||||||||||||||||||||||
|
|||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Human Actin filament-associated protein 1 (aa 1-730 ) |
| AFAP Swiss Prot# | | Q8N556 |
| AFAP Protein names | | Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110) |
| AFAP Gene names | | AFAP1 AFAP |
| Organism | | Homo sapiens (Human) |
| AFAP Entry name | | AFAP1_HUMAN |
| AFAP Codon optimized cDNA(gene) Clone |
| AFAP Cat # | | RPY1799 |
| Tag | | AFAP contains A 6x histidine tag |
| AFAP Formulation | | Liquid |
| AFAP Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| AFAP Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant AFAP Protein |
| AFAP Cat # | | PY1799 |
| AFAP Source | | recombinant |
| AFAP Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| AFAP Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| AFAP Activity | | N/A |
| Tag | | AFAP Contains A 6x histidine tag |
| AFAP Formulation | | Liquid |
| AFAP Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant AFAP Products | | For pricing and availability Click Here >>> |
| AFAP family | | - |
| AFAP Subcellular locations | | Cytoplasm > cytoskeleton. |
| AFAP FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells. |
| AFAP Sequence | | DDBJ | EMBL | GenBank |
| AFAP 3D structure | | ModBase |
| AFAP interaction | | STRING |
| AFAP Proteomic | | PRIDE |
| AFAP Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| AFAP Organism specific | | CTD | MGI |
| AFAP Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| AFAP Gene expression | | Bgee | ArrayExpress | Genevestigator |
| AFAP Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |