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Rat Disks large homolog 4 (aa 1-724 )

Dlgh4 Swiss Prot#

P31016

Dlgh4 Protein names

Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)

Dlgh4 Gene names

Dlg4 Dlgh4 Psd95

Organism

Rattus norvegicus (Rat)

Dlgh4 Entry name

DLG4_RAT

Dlgh4 Codon optimized cDNA(gene) Clone

Dlgh4 Cat #

RPY1781

Tag

Dlgh4 contains A 6x histidine tag

Dlgh4 Formulation

Liquid

Dlgh4 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Dlgh4 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Dlgh4 Protein

Dlgh4 Cat #

PY1781

Dlgh4 Source

recombinant

Dlgh4 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Dlgh4 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Dlgh4 Activity

N/A

Tag

Dlgh4 Contains A 6x histidine tag

Dlgh4 Formulation

Liquid

Dlgh4 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Dlgh4 family

MAGUK family

Dlgh4 Subcellular locations

Cell membrane; Peripheral membrane protein. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Cell junction > synapse > synaptosome.

Dlgh4 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.

Dlgh4 Sequence

DDBJ

EMBL

GenBank

Dlgh4 3D structure

ModBase

Dlgh4 interaction

STRING

Dlgh4 Proteomic

PRIDE

Dlgh4 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Dlgh4 Organism specific

CTD

MGI

Dlgh4 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Dlgh4 Gene expression

Bgee

ArrayExpress

Genevestigator

Dlgh4 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY