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Human Disks large homolog 4 (aa 1-724 )

PSD95 Swiss Prot#

P78352

PSD95 Protein names

Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)

PSD95 Gene names

DLG4 PSD95

Organism

Homo sapiens (Human)

PSD95 Entry name

DLG4_HUMAN

PSD95 Codon optimized cDNA(gene) Clone

PSD95 Cat #

RPY1780

Tag

PSD95 contains A 6x histidine tag

PSD95 Formulation

Liquid

PSD95 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PSD95 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PSD95 Protein

PSD95 Cat #

PY1780

PSD95 Source

recombinant

PSD95 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PSD95 Purity

>90%, as determined by SDS-PAGE under reducing conditions

PSD95 Activity

N/A

Tag

PSD95 Contains A 6x histidine tag

PSD95 Formulation

Liquid

PSD95 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PSD95 family

MAGUK family

PSD95 Subcellular locations

Cell membrane; Peripheral membrane protein. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Cell junction > synapse > synaptosome.

PSD95 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

PSD95 Sequence

DDBJ

EMBL

GenBank

PSD95 3D structure

ModBase

PSD95 interaction

STRING

PSD95 Proteomic

PRIDE

PSD95 Genome annotation

Ensembl

GeneID

KEGG

UCSC

PSD95 Organism specific

CTD

MGI

PSD95 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PSD95 Gene expression

Bgee

ArrayExpress

Genevestigator

PSD95 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY